Rejuran Polynucleotides – Natural Skin Regeneration and Renewal

Rejuran is an innovative skin biorevitalisation treatment based on polynucleotides (PNs) — purified DNA fragments used in aesthetic medicine to stimulate the skin’s natural renewal and regeneration processes.

The aim of Rejuran is not to add volume or alter facial features. Instead, it is designed to improve skin quality, texture, hydration, elasticity and tone, while stimulating the skin’s own regenerative processes.

What Are Polynucleotides?

Polynucleotides are chains made up of repeating units called nucleotides, the basic building blocks of DNA. In aesthetic medicine, they are used as skin regenerators that work through biological processes associated with tissue repair and renewal.

Rejuran polynucleotides are derived from the reproductive cells of wild salmon. They undergo a specialised process of purification, hydrolysis and size selection. The patented DOT™ (DNA Optimizing Technology) enables the production of highly purified, high-molecular-weight polynucleotides.

How Does Rejuran Work?

Polynucleotides participate in cellular regeneration and tissue repair processes. Their effects are associated with:

• Stimulating fibroblast activity.
• Supporting the regeneration of the extracellular matrix and subcutaneous tissue.
• Anti-inflammatory effects.
• Improving skin quality and structure.

The result is not a sudden change in appearance, but a gradual improvement in skin quality. Following a course of treatments, the skin may appear smoother, fresher and more even, with a reduction in the visibility of fine lines, pores and certain types of scars.

Who Is Rejuran Suitable For?

Rejuran is suitable for people who wish to improve their skin quality, particularly if their skin is:

• Thin and sensitive.
• Dry and dehydrated.
• Tired-looking and dull.
• Lacking elasticity and tone.
• Uneven in complexion or prone to hyperpigmentation.
• Affected by prominent fine lines and enlarged pores.

Polynucleotides may also be used to treat certain types of scars, including atrophic, hypertrophic and postoperative scars, as well as for concerns such as under-eye hollows and thinning hair.

Rejuran - Tailored to Different Skin Needs

Rejuran is available in several formulations with different viscosities, allowing the treatment to be tailored to the area being treated.

Rejuran is primarily intended to improve skin elasticity, tone and overall quality. It can be used on the face, neck, décolletage and hands.

Rejuran I is specifically formulated for the delicate eye area and is used to address fine lines, under-eye concerns and mild skin laxity around the eyes (the periorbital area).

Rejuran S has a higher viscosity and is intended for treating scarred areas, including atrophic and hypertrophic scars, as well as acne scars.

What Does the Treatment Involve?

Rejuran is administered intradermally using a very fine needle and a technique involving multiple small injections. Small papules — tiny raised bumps on the skin — may temporarily appear at the injection sites. These are an expected response following treatment.

For the area around the eyes, a specially adapted technique involving superficial intradermal administration is used.

How Many Treatments Are Needed?

For an overall improvement in skin quality, a course of three treatments is recommended, spaced approximately three to four weeks apart. Depending on the individual condition of the skin and the doctor’s assessment, the treatment course may be adjusted. An additional maintenance treatment may also be recommended after six months to help maintain the results achieved.

It is important to note that Rejuran’s effects develop gradually. The aim is not to fill wrinkles immediately or add volume, but to achieve a longer-term improvement in skin quality and vitality.

Why Choose Rejuran?

Rejuran is intended for people who prefer a more natural approach to skin rejuvenation, without changing the shape or defining features of their face. Polynucleotides target skin quality and its regenerative processes, making the treatment suitable for inclusion in combined aesthetic treatment protocols.

Following treatment, the skin may gradually become smoother and more even, with improvements in texture, elasticity and overall appearance.

Rejuran is not a treatment designed to change your face — its goal is to help your skin look healthier, better-quality and more vibrant.

Find out more about our services and prices by browsing our price list or contacting us to arrange an appointment. Our team of specialists is available to answer your questions and provide advice.